Listing code
106.06
Children (Part B)
Body system
106.00
Genitourinary disorders (children)
Subsections
2
Lettered criteria paths
Step in evaluation
3 of 5
Listing match approves the claim
SSA listing text and criteria
Nephrotic syndrome, with A and B:
Subsection A
Laboratory findings as described in 1 or 2, documented on at least two occasions at least 90 days apart during a consecutive 12-month period: Serum albumin of 3.0 g/dL or less, or Proteinuria of 40 mg/m2/hr or greater; AND
Subsection B
Anasarca (see 106.00C3 ) persisting for at least 90 days despite prescribed treatment. Back to Top
Source: SSA Blue Book listing 106.06. Last synced 2026-05-04.
Where claims under 106.06 usually fail
One pitfall is using only a single lab value for albumin or proteinuria, because Subsection A requires results on at least two occasions at least 90 days apart during a consecutive 12-month period. Another pitfall is reporting serum albumin above 3.0 g/dL and proteinuria below 40 mg/m2/hr, since Subsection A requires one of those specific thresholds. A third pitfall is mixing up localized swelling with anasarca, because Subsection B specifically requires anasarca persisting for at least 90 days. A fourth pitfall is timing: Subsection B requires persistence for at least 90 days despite prescribed treatment.
Medical evidence that strengthens this claim
Medical records should document Subsection A with either serum albumin of 3.0 g/dL or less, or proteinuria of 40 mg/m2/hr or greater, on at least two occasions at least 90 days apart within a consecutive 12-month period. Records should also document Subsection B with anasarca persisting for at least 90 days despite prescribed treatment, meaning the swelling continued even while treatment was being given. Because the evidence request across 106.00 focuses on signs, symptoms, and laboratory findings and generally needs coverage for at least 90 days, the file should include treatment records showing the prescribed treatment and response over that period, along with clinical examination findings tied to the swelling.
What happens if your records do not meet this listing
For nephrotic syndrome under 106.06, the criteria are built around Subsection A plus Subsection B. If Subsection A is not met (for example, albumin/proteinuria thresholds not reached or not repeated at the required 90-day spacing), or Subsection B is not met (for example, anasarca did not persist for at least 90 days despite prescribed treatment), the claim typically moves to later steps that evaluate the overall functional impact using the child claimant's residual functional capacity. Even if the exact listing is not met, SSA can still make a decision based on how the condition affects the child's functioning over time.
Work activity and the SGA gate for this condition
This listing itself does not describe a special work standard (SGA) dollar threshold. In any SSDI claim process, work activity is evaluated with the standard SSA concept of substantial gainful activity before a medical listing determination. For nephrotic syndrome specifically, the listing criteria focus on serum albumin/proteinuria thresholds (Subsection A) and anasarca persisting for at least 90 days despite prescribed treatment (Subsection B). If medical evidence supports those criteria, the focus then shifts to whether the child meets the medical listing requirement; once a child is found disabled, eligibility can continue through the trial work period and extended period of eligibility rules that apply after approval (rather than before).
Listing 106.06 FAQ
Questions that come up repeatedly for nephrotic syndrome, with a and b disability claims.