Skip to content
SSAHelper.org

Social Security disability for bone marrow failure disorder: Blue Book listing 107.10

Listing 107.10 is the SSA Blue Book criteria SSA uses for bone marrow failure disorder childhood disability claims. Meeting it at step 3 of the disability evaluation approves the claim without further analysis of past work or other jobs in the national economy. This page covers what SSA looks for, the medical evidence the criteria require, and what happens if your records don't quite match.

Listing code

107.10

Children (Part B)

Body system

107.00

Hematological disorders (children)

Subsections

0

No lettered criteria

Step in evaluation

3 of 5

Listing match approves the claim

SSA listing text and criteria

Disorders of bone marrow failure, including myelodysplastic syndromes, aplastic anemia, granulocytopenia, and myelofibrosis (see 107.00E ), with: Complications of bone marrow failure requiring at least three hospitalizations within a 12-month period and occurring at least 30 days apart. Each hospitalization must last at least 48 hours, which can include hours in a hospital emergency department immediately before the hospitalization (see 107.00E2 ). OR Myelodysplastic syndromes or aplastic anemias requiring life-long RBC transfusions at least once every 6 weeks to maintain life (see 107.00E3 ).

This listing has no lettered subsections. The diagnosis itself, supported by the medical evidence described in the body-system overview, is what SSA evaluates.

Source: SSA Blue Book listing 107.10. Last synced 2026-05-04.

Where claims under 107.10 usually fail

One failure mode is meeting a diagnosis label (like myelodysplastic syndrome or aplastic anemia) but not meeting either the hospitalization pattern or the transfusion pattern required for 107.10. Another is counting hospital stays incorrectly, because each hospitalization must last at least 48 hours, and the timing must be at least 30 days apart. A third pitfall is trying to satisfy the rule with fewer than three hospitalizations in a 12-month period. A fourth pitfall is applying the transfusion rule to other bone marrow failure diagnoses; the lifelong transfusion requirement is stated for myelodysplastic syndromes or aplastic anemias.

Medical evidence that strengthens this claim

Medical evidence needs to establish a hematological disorder using a laboratory report of a definitive test signed by a physician, or a laboratory report plus a physician statement, or a persuasive physician report that confirms the diagnosis using appropriate laboratory analysis or other diagnostic methods and includes the results or explains how the diagnosis was established. For the hospitalization pathway, the record should support that there were at least three hospitalizations within 12 months, each lasting at least 48 hours (including time in the emergency department immediately before the hospitalization), with at least 30 days between hospitalizations. For the lifelong transfusion pathway, documentation should show myelodysplastic syndromes or aplastic anemia requiring lifelong red blood cell transfusions at least once every 6 weeks to maintain life.

What happens if your records do not meet this listing

If the required hospitalization pattern (at least three hospitalizations within 12 months, at least 48 hours each, at least 30 days apart) or the lifelong transfusion pattern (myelodysplastic syndromes or aplastic anemia with red blood cell transfusions at least every 6 weeks to maintain life) is not met, the case typically will move to the next step in the childhood disability evaluation. At that point, SSA still assesses how the medical impairment affects functioning using the full medical picture rather than only the strict 107.10 triggers.

Work activity and the SGA gate for this condition

SSA uses the substantial gainful activity concept in disability cases for everyone, including children applying under Part B. For 107.10 specifically, the criteria emphasize serious complications from bone marrow failure, such as at least three hospitalizations within 12 months lasting at least 48 hours each (with at least 30 days between), or lifelong red blood cell transfusions at least once every 6 weeks for myelodysplastic syndromes or aplastic anemia. Those kinds of frequent, ongoing medical complications often make sustained work activity difficult, but whether activity is considered disqualifying depends on the case facts and SSA's childhood disability evaluation steps rather than only the diagnostic label or the presence of one hospitalization. For children found eligible, ongoing eligibility can continue based on improvement and other continuing disability rules after approval,

Listing 107.10 FAQ

Questions that come up repeatedly for disorders of bone marrow failure, including myelodysplastic syndromes, aplastic anemia, granulocytopenia, and myelofibrosis disability claims.