Listing code
107.05
Children (Part B)
Body system
107.00
Hematological disorders (children)
Subsections
0
No lettered criteria
Step in evaluation
3 of 5
Listing match approves the claim
SSA listing text and criteria
Hemolytic anemias, including sickle cell disease, thalassemia, and their variants (see 107.00C ), with: Documented painful (vaso-occlusive) crises requiring parenteral (intravenous or intramuscular) narcotic medication, occurring at least six times within a 12-month period with at least 30 days between crises. OR Complications of hemolytic anemia requiring at least three hospitalizations within a 12-month period and occurring at least 30 days apart. Each hospitalization must last at least 48 hours, which can include hours in a hospital emergency department or comprehensive sickle cell disease center immediately before the hospitalization (see 107.00C2 ). OR Hemoglobin measurements of 7.0 grams per deciliter (g/dL) or less, occurring at least three times within a 12-month period with at least 30 days between measurements. OR Beta thalassemia major requiring life-long RBC transfusions at least once every 6 weeks to maintain life (see 107.00C4 ). E. Congestive heart failure, cerebrovascular damage, or emotional disorder as described under the criteria in 104.02, 111.00ff, or 112.00ff. --> 107.06 Chronic idiopathic thrombocytopenic purpura of childhood . With purpura and thrombocytopenia of 40,000 platelets/cu.mm. or less despite prescribed therapy or recurrent upon withdrawal of treatment. -->
This listing has no lettered subsections. The diagnosis itself, supported by the medical evidence described in the body-system overview, is what SSA evaluates.
Source: SSA Blue Book listing 107.05. Last synced 2026-05-04.
Where claims under 107.05 usually fail
One pitfall is having a hemolytic anemia diagnosis but missing the required frequency and timing, such as painful vaso-occlusive crises at least six times in 12 months with at least 30 days between crises, or hospitalizations at least three times in 12 months with at least 30 days between them. Another pitfall is having emergency or clinic visits that do not rise to the listing's required hospitalizations that last at least 48 hours. A third pitfall is using hemoglobin numbers that do not match the threshold (7.0 g/dL or less) and the required pattern of at least three measurements in a 12-month period with at least 30 days between measurements. A fourth pitfall is beta thalassemia major without the specific transfusion requirement of at least once every 6 weeks to maintain life.
Medical evidence that strengthens this claim
SSA needs evidence that establishes a hematological disorder, including hemolytic anemia, from a definitive laboratory report signed by a physician, or a definitive laboratory report not signed by a physician plus a physician report stating the disorder, or (if no definitive lab report is available) a persuasive physician report confirming the diagnosis by appropriate testing with the results stated. For the severity part, records should show the required clinical events or measurements that match the listing: parenteral (IV or IM) narcotic treatment during documented painful vaso-occlusive crises, counts of crises and timing between crises, hospital stay duration of at least 48 hours (including appropriate permitted pre-hospital emergency/comprehensive sickle cell center hours), hemoglobin values at or below 7.0 g/dL with timing between measurements, or for beta thalassemia major documentation of lifelong red blood cell transfusions at least once every 6 weeks.
What happens if your records do not meet this listing
This listing sets out clear medical thresholds, so if those specific crisis, hospitalization, hemoglobin, or transfusion requirements are not met, the claim generally moves to the next steps in the evaluation process rather than being approved under this exact listing. In practice, a residual functional capacity (RFC) assessment is used to describe what the child can still do despite symptoms, and the decision then considers whether the child's limitations still prevent age-appropriate functioning. For children, age and functional impact are still part of the overall disability determination even when a listing is not met.
Work activity and the SGA gate for this condition
For SSDI, work activity is evaluated at the start of the claim, and eligibility is affected by whether the child is engaging in substantial work activity. For benefits after approval, the SSA process includes the trial work period and then an extended period of eligibility for those who meet the disability requirements under this listing. This listing also contains specific severity indicators like painful vaso-occlusive crises requiring parenteral narcotic medication at least six times in 12 months (with at least 30 days between crises), repeated hospitalizations, repeated hemoglobin measurements at 7.0 g/dL or less, or beta thalassemia major requiring transfusions at least once every 6 weeks, which reflect substantial medical limits.
Listing 107.05 FAQ
Questions that come up repeatedly for hemolytic anemias, including sickle cell disease, thalassemia, and their variants disability claims.