Listing code
14.07
Adult (Part A)
Body system
14.00
Immune system disorders
Subsections
3
Lettered criteria paths
Step in evaluation
3 of 5
Listing match approves the claim
SSA listing text and criteria
Immune deficiency disorders, excluding HIV infection . As described in 14.00E . With:
Subsection A
One or more of the following infections. The infection(s) must either be resistant to treatment or require hospitalization or intravenous treatment three or more times in a 12-month period. 1. Sepsis; or 2. Meningitis; or 3. Pneumonia; or 4. Septic arthritis; or 5. Endocarditis; or 6. Sinusitis documented by appropriate medically acceptable imaging. OR
- Sepsis; or
- Meningitis; or
- Pneumonia; or
- Septic arthritis; or
- Endocarditis; or
- Sinusitis documented by appropriate medically acceptable imaging. OR
Subsection B
Stem cell transplantation as described under 14.00E3 . Consider under a disability until at least 12 months from the date of transplantation. Thereafter, evaluate any residual impairment(s) under the criteria for the affected body system. OR
Subsection C
Repeated manifestations of an immune deficiency disorder, with at least two of the constitutional symptoms or signs (severe fatigue, fever, malaise, or involuntary weight loss) and one of the following at the marked level: 1. Limitation of activities of daily living. 2. Limitation in maintaining social function. 3. Limitation in completing tasks in a timely manner due to deficiencies in concentration, persistence, or pace. Back to Top
- Limitation of activities of daily living.
- Limitation in maintaining social function.
- Limitation in completing tasks in a timely manner due to deficiencies in concentration, persistence, or pace. Back to Top
Source: SSA Blue Book listing 14.07. Last synced 2026-05-04.
Where claims under 14.07 usually fail
A common failure is matching an infection diagnosis name but not meeting the 12-month threshold tied to hospitalization or intravenous treatment three or more times, and not showing treatment resistance as the listing requires. Another failure is treating any sinus problem as qualifying when the criterion specifically requires sinusitis documented by appropriate medically acceptable imaging. A third failure is trying to qualify under Subsection C using only one constitutional symptom or sign, because at least two (severe fatigue, fever, malaise, or involuntary weight loss) are required. A fourth failure is having symptoms but not having the required functional limitation at a marked level in Subsection C for activities of daily living, social function, or timely task completion due to concentration, persistence, or pace.
Medical evidence that strengthens this claim
Evidence should clearly connect the immune deficiency disorder to qualifying episodes or treatment. For Subsection A, medical records should show one or more of the listed infections (sepsis, meningitis, pneumonia, septic arthritis, endocarditis, or sinusitis) and also document either resistance to treatment or that hospitalization or intravenous treatment occurred at least three times within a 12-month period. For sinusitis under Subsection A, documentation should include the imaging basis (the listing requires sinusitis documented by appropriate medically acceptable imaging). For Subsection B, records should document that stem cell transplantation occurred as described under 14.00E3, because the timing rule depends on the transplant date. For Subsection C, documentation should show repeated immune deficiency manifestations plus at least two constitutional symptoms or signs from severe fatigue, fever, malaise, and involuntary weight loss, along with the marked-level functional limitations in one of the three areas: activities of daily living, maintaining social function, or timely (
What happens if your records do not meet this listing
If Subsection A, B, or C is not met as written, the claim can still be decided using the overall functional impact. Step 4 considers the ability to do past work, and Step 5 considers whether other work is possible based on residual functional capacity. The listing's specific infection pattern, transplant timing, or the symptom-plus-marked-function pattern can strongly affect residual functional capacity, but approval can still occur through the broader functional evaluation even when a person does not exactly match one of the lettered criteria.
Work activity and the SGA gate for this condition
For SSDI, the start of the claim includes an SGA work activity gate. If there is substantial gainful activity, eligibility can be affected even if the immune deficiency disorder is serious. For people who are evaluated under 14.07B after stem cell transplantation, evaluation continues for at least 12 months from the transplant date under the listing's pathway, and after that point any residual impairments are evaluated under the criteria for the affected body system. After any approval, continued eligibility turns on whether work and other continuing-impairment rules are met for the same overall condition and resulting functional limits; the listing's functional limitations tied to activities of daily living, social function, and concentration, persistence, or pace are the types of effects that typically matter.
Listing 14.07 FAQ
Questions that come up repeatedly for immune deficiency disorders, excluding hiv infection disability claims.